About
Michael Isaac
Chief Product Officer at SynapseDx. Three decades turning chaos into cash flows for Fortune 500s, AI startups, and the teams who build them.
Three decades. One playbook.
Started coding at 12 on a Commodore 64. Built my first company at 25. Led thousand-person teams at Avanade by 40. Exited my latest venture at 55.
Today my day job is Chief Product Officer at SynapseDx, building enterprise AI infrastructure for Fortune 500s. MPIsaac Ventures is my personal brand. Through it I take select advisory engagements and back early-stage AI ventures — healthcare, fintech, enterprise. If data can transform it, I'm interested.
Instrument-rated pilot. Scotch enthusiast. Grandpa to 5 girls. I still wish I held the 1983 world record for Atari Seaquest.
The highlights reel
- Drove 27% revenue growth for a Fortune 100 with analytics
- Led global teams generating $50M+ a year
- Designed data strategies across healthcare, aerospace, and finance
- Built ISAAC — an AI coding engine that cuts errors by 40%
- Built Coherence Gateway — turns any API into an AI-ready tool in 60 seconds
The numbers
$100M+
In enterprise value driven across Fortune 500 transformations.
2 exits
Most recently Conclusn, acquired in 2024.
30 years
From CFD simulations to LLMs. From Commodore 64 to Claude.
What I work on
- Enterprise AI infrastructure
- Insurance & financial-services AI
- Healthcare data and clinical insights
- Digital transformation at Fortune 500 scale
- Venture building and AI investing
- Global delivery and team leadership
Where I show up
Day job
Chief Product Officer, SynapseDx
Building enterprise AI infrastructure for Fortune 500s — Atlas (orchestration), Coherence (tool gateway), and ISAAC (AI coding platform).
Personal brand
MPIsaac Ventures
Vehicle for select advisory engagements and early-stage AI investing across healthcare, fintech, and enterprise.